Lane marking detection is fundamental for both advanced driving assistance systems and traffic surveillance systems.However, detecting lane is highly challenging when the visibility of a road lane marking is low, obscured or often invisible due to real-life challenging environment and adverse weather.Most of the lane detection methods suffer from f
A Global Climatology of Explosive Cyclones using a Multi-Tracking Approach
In this study, hemispheric climatologies of explosive cyclones (ECs) derived using a set of different cyclone detection and tracking IMMUNOCARE methods (CDTMs) are analysed.The aim is to evaluate trends and regional characteristics of ECs discussing consensus and disagreement among methods.Areas of both hemispheres characterised by relatively frequ
A Physiologically Based Pharmacokinetic Framework for Quantifying Antibody Distribution Gradients from Tumors to Tumor-Draining Lymph Nodes
Immune checkpoint blockades prescribed in the neoadjuvant setting are now under active investigation for many types of tumors, and many have shown early success.The primary tumor (PT) and tumor-draining lymph node (TDLN) immune factors, along with adequate therapeutic antibody distributions to the PT and TDLN, are critical for optimal immune activa
Insights into the Binding of 3-(1-Phenylsulfonyl-2-methylindol-3-ylcarbonyl) Propanoic Acid to Bovine Serum Albumin: Spectroscopy and Molecular Modelling Studies
Serum albumin is a globular protein which is most abundant in human that binds remarkably with wide range of drugs.A Womens Boardshoarts reliable prediction of protein and drug binding at the atomic level by optical spectroscopy and molecular modeling methods provides the basis for the design of new drug compounds.In the current study, A newly synt